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ACRIDINE
Traducere în limba română
acridine substantiv
(chim.) acridină.
Exemple de propoziții și/sau fraze:
Acridine antineoplastic agent used in mammary and ovarian tumors.
(Nitracrine, NLM, Medical Subject Headings)
An immunomodulator, 3,6-bis(2-piperidinoethoxy) acridine trihydrochloride, used in a phase I study for possible immunostimulatory effects in colorectal cancer.
(CL 246738, NCI Thesaurus)
Benz[a,h]acridine is primarily found in petroleum refinery incinerator emissions, coal combustion emissions, cigarette smoke and coal tar pitch.
(Dibenz[a,h]acridine, NCI Thesaurus)
Dibenz[a,j]acridine is primarily found in gasoline exhaust, petroleum refinery incinerator emissions, coal combustion emissions, cigarette smoke and coal tar pitch.
(Dibenz[a,j]acridine, NCI Thesaurus)
Acridine and its derivatives intercalate within DNA and RNA by forming hydrogen-bonds and stacking between base pairs resulting in DNA crosslinks and strand breaks.
(Acridine, NCI Thesaurus)
A natural alkaloid with an acridine structure isolated from the bark of the plant Acronychia baueri (Australian scrub ash) with antineoplastic properties.
(Acronine, NCI Thesaurus)
Acridine carboxamide inhibits both topoisomerases I and II and intercalates into DNA, resulting in DNA damage, the disruption of DNA repair and replication, the inhibition of RNA and protein synthesis, and cell death.
(Acridine carboxamide, NCI Thesaurus)
A microscopy staining method that utilizes acridine orange, a fluorescent cationic dye that is selective for nucleic acids, to determine the presence of viable cells or microorganisms in a sample.
(Acridine Orange Staining Method, NCI Thesaurus)
Although the exact relationship between DNA binding and its activity has yet to be fully elucidated, amsacrine intercalates DNA through its acridine moiety, and its nonintercalative headgroup impedes topoisomerase II activity, augmenting enzyme-mediated DNA cleavage and resulting in DNA double-strand breaks.
(Amsacrine Lactate, NCI Thesaurus)
Also called acridine carboxamide.
(DACA, NCI Dictionary)
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