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    ANALOGUE

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    Traducere în limba română

    analogue substantiv

    1. expresie analogă.

    2. (tehn.) analog.

     Exemple de propoziții și/sau fraze: 

    An auristatin analogue immunoconjugate directed against Eph receptor A2 (EphA2)-positive cancer cells with potential antineoplastic activity.

    (Anti-EphA2 Monoclonal Antibody-MMAF Immunoconjugate MEDI-547, NCI Thesaurus)

    The study led authors to present this place as an example of the limits that life can support, and even to propose it as a terrestrial analogue of early Mars.

    (Place discovered on earth with no microbial life, Editura Global Info)

    Such a planet has no analogue in our solar system and is rare even within the thousands of exoplanets discovered to date.

    (Multiple metals – and possible signs of water – found in unique exoplanet, University of Cambridge)

    A synthetic muramyl dipeptide (MDP) analogue with potential immunostimulating and antineoplastic activity.

    (Almurtide, NCI Thesaurus)

    Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis.

    (Anthracycline Analogue GPX-150, NCI Thesaurus)

    An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody, directed against the extracellular domain of the human CD70 molecule, conjugated to a prodrug of a CC-1065 (rachelmycin) analogue via a stable peptide-based linker, with potential antineoplastic activity.

    (Anti-CD70 Antibody-Drug Conjugate MDX-1203, NCI Thesaurus)

    As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis.

    (Aminopterin, NCI Thesaurus)




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