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ANTIGEN

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(GB):

Traducere în limba română

antigen substantiv

(med.) antigen.

 Exemple de propoziții și/sau fraze: 

A soluble fusion protein consisting of the extracellular domain of human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) linked to a modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1) with immunosuppressive activity.

(Abatacept, NCI Thesaurus)

A cancer vaccine consisting of a recombinant adenoviral vector encoding the tumor-associated antigen (TAA) human MUC-1 (hMUC-1) linked to the extracellular domain (ecd) of the co-stimulatory molecule CD40 ligand (CD40L) and an adenovirus signal sequence that encodes a secretory signal peptide (Ad-sig) with potential immunostimulating and antineoplastic activities.

(Ad-sig-hMUC-1/ecdCD40L Vaccine, NCI Thesaurus)

Subsequently, the Fc component of the engineered antibody targets and binds to the CD64 receptor on the dendritic cells (DCs); upon processing by DCs, the cellular immune system may be activated to induce helper T-cell and CTL immune responses against tumor cells expressing the TRP2 antigen.

(Melanoma TRP2 CTL Epitope Vaccine SCIB1, NCI Thesaurus)

A cancer vaccine consisting of a peptide derived from the melanocyte differentiation antigen Melan-A (or MART-1) and the human leukocyte antigen HLA-DP4-restricted human melanoma antigen 3 (MAGE-3.DP4), with potential immunostimulating and antineoplastic activities.

(Melan-A/MAGE-3.DP4 Peptide Vaccine, NCI Thesaurus)

Upon exposure to the tumor-associated antigens (TAA) released from dying glioma cells, which were killed by thymidine kinase-mediated valacyclovir-induced tumor cell death, the DCs initiate a specific immune response against any remaining TAA-expressing tumor cells.

(Ad-hCMV-Flt3L, NCI Thesaurus)

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