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    BINDING

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    Traducere în limba română

    binding I. substantiv

    1. legătură, legare.

    2. bandaj.

    3. copertă.

    4. tiv.

    5. (sport) întărire.

    binding II. adjectiv

    1. liant, care leagă.

    2. obligator, care angajează, cu caracter de obligativitate;

    in a binding form într-o formă obligatorie.

     Exemple de propoziții și/sau fraze: 

    Actin-binding protein anillin (1124 aa, ~124 kDa) is encoded by the human ANLN gene.

    (Actin-Binding Protein Anillin, NCI Thesaurus)

    Toxin binding changes its color from blue to red, and the intensity of red fluorescence increases with the amount of toxin bound.

    (3-D gel-nanoparticle device detoxifies blood, NIH)

    Major depression, obesity and chronic pain are all linked to the effects of one protein, called "FK506-binding protein 51," or FKBP51.

    (Depression, Obesity, Chronic Pain Could be Treated by Targeting the Same Key Protein, Editura Global Info)

    A team of scientists identified a number of mutations (changes in the DNA sequence) centred around a protein known as a penicillin-binding protein 2a or PBP2a.

    (Widely-available antibiotics could be used in the treatment of ‘superbug’ MRSA, University of Cambridge)

    MET receptor tyrosine kinase inhibitor SGX523 specifically binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.

    (MET Tyrosine Kinase Inhibitor SGX523, NCI Thesaurus)

    On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).

    (ABC Transporter Pathway, NCI Thesaurus/KEGG)

    MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.

    (MET Tyrosine Kinase Inhibitor BMS-777607, NCI Thesaurus)




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