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CONJUGATE
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Traducere în limba română
conjugate I. verb A. tranzitiv
(gram.) a conjuga.
conjugate I. verb B. intranzitiv
(biol.) a se împreuna, a se însoţi, a se împerechea.
conjugate II. adjectiv
1. împreunat, unit, cuplat; conjugat, îmbinat, combinat; (fiz., fiziol.) conjugat.
2. (bot. despre fructe) împerecheat.
3. (lingv. despre cuvinte) cu aceeaşi rădăcină.
4. (biol.) contopit, fuzionat.
conjugate III. substantiv
(lingv.) derivat, cuvânt cu aceeaşi rădăcină.
Exemple de propoziții și/sau fraze:
Anti-CD19-DM4 conjugate SAR3419 targets the cell surface antigen CD19, found on a number of B-cell-derived cancers.
(Anti-CD19-DM4 Immunoconjugate SAR3419, NCI Thesaurus)
The monoclonal antibody portion of the anti-CD33 monoclonal antibody-drug conjugate SGN-CD33A specifically binds to the cell surface antigen CD33.
(Anti-CD33 Antibody-Drug Conjugate SGN-CD33A, NCI Thesaurus)
An immunoconjugate consisting of a humanized monoclonal antibody against the tumor-associated sialoglycotope CA6 (huDS6) conjugated to the cytotoxic maytansinoid DM4, with potential antineoplastic activity.
(Anti-CA6-DM4 Immunoconjugate SAR566658, NCI Thesaurus)
Adcetris is a type of antibody-drug conjugate.
(Adcetris, NCI Dictionary)
Ado-trastuzumab emtansine is a type of antibody-drug conjugate.
(Ado-trastuzumab emtansine, NCI Dictionary)
An immunoconjugate consisting of the humanized monoclonal antibody huMy9-6 conjugated to the cytotoxic maytansinoid DM4 with potential antineoplastic activity.
(Anti-CD33 Monoclonal Antibody-DM4 Conjugate AVE9633, NCI Thesaurus)
An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody, directed against the extracellular domain of the human CD70 molecule, conjugated to a prodrug of a CC-1065 (rachelmycin) analogue via a stable peptide-based linker, with potential antineoplastic activity.
(Anti-CD70 Antibody-Drug Conjugate MDX-1203, NCI Thesaurus)
By binding to proteoglycan chondroitin sulfate-associated protein, monoclonal antibody Me1-14 F(ab')2 conjugated to a radioisotope may localize gliomas and melanomas when used as a tracer in radioimaging applications; in radioimmunotherapeutic applications, this agent conjugated to a radioisotope may be used to deliver targeted radiotoxicity to these tumors.
(Monoclonal Antibody Me1-14 F(ab')2, NCI Thesaurus)
Upon administration of a biotin-based radioconjugate, the biotin moiety of the radioconjugate binds to the streptavidin moiety of anti-CD45 BC8 antibody-streptavidin conjugate and, upon cellular internalization, specifically delivers cytotoxic radiation to CD45-expressing tumor cells.
(Anti-CD45 BC8 Monoclonal Antibody-Streptavidin Conjugate, NCI Thesaurus)
An immunoconjugate consisting of a humanized monoclonal antibody that is engineered to contain cysteine residues that are conjugated to the synthetic, DNA cross-linking, pyrrolobenzodiazepine dimer SGD-1882, via the protease-cleavable linker maleimidocaproyl-valine-alanine dipeptide, with potential antineoplastic activity.
(Anti-CD33 Antibody-Drug Conjugate SGN-CD33A, NCI Thesaurus)
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