Editura Global Info / Dicţionar englez-român

DEFECTIVE

Pronunție (USA):

(GB):

Traducere în limba română

defective I. adjectiv

1. defectuos, imperfect, incomplet.

2. defectuos; deteriorat, cu cusururi, defect; slab.

3. (gram.) defectiv.

defective II. substantiv

1. lucru defect.

2. om cu defecte (mai ales fizice).

 Exemple de propoziții și/sau fraze: 

But in people with cystic fibrosis, this protein is defective and the cells do not release the chloride.

(Diagnosing cystic fibrosis with wearable devices, NIH)

In a series of experiments that examined the interaction between Alda-1 and the defective ALDH2 enzyme, Dr. Hurley and his colleagues found that Alda-1 restored the structure of the inactive enzyme.

(Alcohol Could be Toxic and Cause DNA Damage for Some People, NIH, US)

A replication-defective, recombinant oncolytic adenovirus encoding human endostatin with potential antineoplastic activity.

(Adenovirus Encoding Recombinant Human Endostatin, NCI Thesaurus)

As integral components of the late G1 restriction point, the Rb gene product and p16 are negative regulators of the cell cycle; ovarian cancer cells and non-small cell lung cancer cells may be defective in the Rb/p16 pathway.

(Oncolytic Ad5-Delta 24RGD, NCI Thesaurus)

Part of the reason why those cells are defective in the differentiation program, which would mean that they would stop dividing, is that the β-catenin complex is being degraded in those cells because of an anomaly in the signaling pathway that controls that.

(New Genes Found Responsible for Regulating Muscle Cells, Editura Global Info)

If this be true (and they affirm it with great confidence) it is much to be wished, that their observations were made public, whereby the theory of comets, which at present is very lame and defective, might be brought to the same perfection with other arts of astronomy.

(Gulliver's Travels into several remote nations of the world, de Jonathan Swift)

A cancer vaccine consisting of a replication-defective recombinant canarypox virus [ALVAC(2)] encoding the cancer-testis antigen NY-ESO and the TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; also called TRICOM), with potential immunostimulatory and antineoplastic activities.

(ALVAC(2)-NY-ESO-1 (M)/TRICOM Vaccine, NCI Thesaurus)

Selectively replication competent in cells that are defective in retinoblastoma gene (Rb) or cyclin-dependent kinase inhibitor-2A (p16), active replication of oncolytic adenovirus Ad5-Delta 24RGD in tumor cells may induce oncolysis or cell lysis.

(Oncolytic Ad5-Delta 24RGD, NCI Thesaurus)

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