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DEMETHYLATION

Traducere în limba română

demethylation substantiv

(chim.) demetilare.

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This protein is involved in the demethylation of histone H3.

(Lysine-Specific Demethylase 6A, NCI Thesaurus)

This protein plays a role in both histone demethylation and the positive regulation of gene transcription.

(Lysine-Specific Demethylase 5A, NCI Thesaurus)

This protein is involved in both demethylation of histone H3 and regulation of cellular differentiation.

(Lysine-Specific Demethylase 6B, NCI Thesaurus)

This protein is involved in both histone demethylation and transcriptional regulation.

(Lysine-Specific Histone Demethylase 1, NCI Thesaurus)

Although the exact mechanism of action has yet to be fully elucidated, parconazole, like other azole antifungals, most likely inhibits the cytochrome P450 dependent 14 alpha demethylation of lanosterol.

(Parconazole, NCI Thesaurus)

Although the exact mechanism of action has yet to be fully elucidated, oxiconazole, like other azole antifungals, most likely inhibits the cytochrome P450-dependent demethylation of lanosterol.

(Oxiconazole, NCI Thesaurus)

This allele, which encodes lysine-specific demethylase 6B protein, is involved in both histone demethylation and cellular differentiation.

(KDM6B wt Allele, NCI Thesaurus)

This gene plays a role in both cellular differentiation and histone demethylation.

(KDM6B Gene, NCI Thesaurus)

Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage.

(Altretamine, NCI Thesaurus)

Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols, the loss of normal fungal sterols, and fungistatic activity.

(Fluconazole, NCI Thesaurus)

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