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    DENDRITIC

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    dendritic(al) adjectiv

    (mat., mineral.) dendritic, arborescent.

     Exemple de propoziții și/sau fraze: 

    This gene may be involved in the regulation of dendritic cells.

    (PLAC8 Gene, NCI Thesaurus)

    Upon administration, allogeneic dendritic cell-myeloma idiotype vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against myeloma cells, resulting in cell lysis.

    (Allogeneic Dendritic Cell-Myeloma Idiotype Vaccine, NCI Thesaurus)

    Plasmacytoid dendritic cells (pDCs) express a characteristic set of surface markers, such as CD123 (interleukin-3 receptor alpha chain), BDCA-2 (blood dendritic cell antigen 2; CD303) and BDCA-4 (CD304), as well as intracellular toll-like receptors 7 and 9.

    (Plasmacytoid Dendritic Cell Vaccine, NCI Thesaurus)

    Upon administration allogeneic glioblastoma stem-like cell line lysate-pulsed autologous dendritic cell vaccine exposes the immune system to GBM stem cell antigens, which may result in cytotoxic T lymphocyte (CTL) and antibody responses against GBM cells.

    (Allogeneic Glioblastoma Stem-like Cell Line Lysate-pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)

    A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding three full length human melanoma associated antigens (MAAs), tyrosinase, melan-A (MART-1) and the melanoma antigen A6 (MAGEA6), with potential antineoplastic activity.

    (Adenovirus Encoding Tyrosinase/MART-1/MAGEA6-transduced Autologous Dendritic Cell Vaccine, NCI Thesaurus)

    Vaccination with Ad5F35-LMP1/LMP2-transduced autologous dendritic cells may stimulate a specific cytotoxic T-lymphocyte (CTL) response against LMP1- and LMP2-expressing tumor positive cells, resulting in tumor cell lysis and inhibition of tumor cell proliferation.

    (Ad5F35-LMP1/LMP2-Transduced Autologous Dendritic Cells, NCI Thesaurus)

    Follicular dendritic cells have Fc receptors (RECEPTORS, FC) and C3b receptors (RECEPTORS, COMPLEMENT 3B), but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T-cells.

    (Murine Follicular Dendritic Cells, NLM, Medical Subject Headings)

    Subsequently, the Fc component of the engineered antibody targets and binds to the CD64 receptor on the dendritic cells (DCs); upon processing by DCs, the cellular immune system may be activated to induce helper T-cell and CTL immune responses against tumor cells expressing the TRP2 antigen.

    (Melanoma TRP2 CTL Epitope Vaccine SCIB1, NCI Thesaurus)

    Upon ex vivo stimulation and expansion of the precursor cells into mature, fully functional dendritic cells (DCs) and subsequent administration, the allogeneic AML antigen-expressing DC vaccine may elicit a potent cytotoxic T-cell (CTL) and antibody response against AML antigen-expressing cells, resulting in tumor cell death.

    (Allogeneic AML Antigen-expressing Dendritic Cell Vaccine, NCI Thesaurus)




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