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DISRUPT

Pronunție (USA): (GB):

Traducere în limba română

disrupt I. verb tranzitiv

1. a rupe, a sfărâma, a separa cu forţa.

2. a dezbina, a produce o ruptură / o sciziune în, a scinda;

to disrupt the unity a sparge unitatea.

disrupt II. part. trec. de la disrupt (în loc de disrupted).

Exemple de propoziții și/sau fraze:

In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR-2), thereby disrupting tumor angiogenesis.

(B-Raf/VEGFR-2 Inhibitor RAF265, NCI Thesaurus)

Oncogene FGR disrupts normal cell function.

(Oncogene FGR, NCI Thesaurus)

They can change, disrupt or amplify genes, or have no effect at all.

(Harnessing tomato jumping genes could help speed-breed drought-resistant crops, University of Cambridge)

Oncogene HST disrupts normal cell function.

(Oncogene HST, NCI Thesaurus)

Oncogene FPS-FES disrupts normal cell function.

(Oncogene FPS-FES, NCI Thesaurus)

Oncogene ERBB2 disrupts normal cell function.

(Oncogene ErbB2, NCI Thesaurus)

Oncogene EGF disrupts normal cell function.

(Oncogene EGF, NCI Thesaurus)

The monoclonal antibody portion of anti-CD33 monoclonal antibody-DM4 conjugate AVE9633 specifically binds to the cell surface antigen CD33 expressed on myeloid leukemia cells; upon internalization, the DM4 moiety is released, binds tubulin, and disrupts microtubule assembly/disassembly dynamics, resulting in the inhibition of cell division and cell growth in myeloid leukemia cells that express CD33.

(Anti-CD33 Monoclonal Antibody-DM4 Conjugate AVE9633, NCI Thesaurus)

Upon antibody/antigen binding and internalization, the immunoconjugate releases DM4, which binds to tubulin and disrupts microtubule assembly/disassembly dynamics, resulting in inhibition of cell division and cell growth of CA6-expressing tumor cells.

(Anti-CA6-DM4 Immunoconjugate SAR566658, NCI Thesaurus)

(Anti-CD19-DM4 Immunoconjugate SAR3419, NCI Thesaurus)

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