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DOMAIN

Pronunție (USA):

(GB):

Traducere în limba română

domain substantiv

1. domeniu, proprietate, moşie; teritoriu.

2. sferă (de influenţă etc.), domeniu (al unei ştiinţe), câmp, sector (de activitate).

◊ (jur.) Eminent Domain dreptul suveran al statului asupra tuturor proprietăţilor, drept de expropriere / de naţionalizare.

 Exemple de propoziții și/sau fraze: 

ADAMs are transmembrane proteins containing both a disintegrin and a metalloprotease domain.

(ADAM Type Metalloprotease Domain, NCI Thesaurus)

Outside was the common domain of all gods—the roads and streets.

(White Fang, de Jack London)

This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to almost the entire GMP synthase [glutamine-hydrolyzing] protein.

(MLL/GMPS Fusion Protein, NCI Thesaurus)

A soluble fusion protein consisting of the extracellular domain of human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) linked to a modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1) with immunosuppressive activity.

(Abatacept, NCI Thesaurus)

This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to the C-terminal proline-rich region and ubiquitin-binding leucine zipper domain of the E3 ubiquitin-protein ligase CBL protein.

(MLL/CBL Fusion Protein, NCI Thesaurus)

On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).

(ABC Transporter Pathway, NCI Thesaurus/KEGG)

This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused with the C-terminal SH3 domain of the LIM and SH3 domain protein 1.

(MLL/LASP1 Fusion Protein, NCI Thesaurus)

A cancer vaccine consisting of a recombinant adenoviral vector encoding the tumor-associated antigen (TAA) human MUC-1 (hMUC-1) linked to the extracellular domain (ecd) of the co-stimulatory molecule CD40 ligand (CD40L) and an adenovirus signal sequence that encodes a secretory signal peptide (Ad-sig) with potential immunostimulating and antineoplastic activities.

(Ad-sig-hMUC-1/ecdCD40L Vaccine, NCI Thesaurus)

This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to the N-terminus of the entire protein AF1q.

(MLL/MLLT11 Fusion Protein, NCI Thesaurus)

This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to the C-terminal leucine zipper domain of protein AF-10.

(MLL/MLLT10 Fusion Protein, NCI Thesaurus)

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