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    GALLIUM

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    gallium substantiv

    (chim.) galiu.

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    It is also taken up by several tumors, thus gallium scintigraphy can be used for the staging of tumors.

    (Gallium scan, NCI Thesaurus)

    Similar to octreotide, gallium Ga 68-edotreotide binds to SSTRs, especially type 2 receptors, present on the cell membranes of many types of neuroendocrine tumor cells and their metastases, thereby allowing for imaging of SSTR-expressing cells upon PET.

    (Gallium Ga 68-Edotreotide, NCI Thesaurus)

    After pretargeting with a bispecific monoclonal antibody (BiMoAB) directed against both a tumor associated antigen (TAA) and the HSG hapten-peptide, the HSG portion of administered gallium Ga 68-labeled di-HSG-DOTA peptide IMP-288 binds the anti-HSG portion of the BiMoAB; Ga-68 radioisotopic activity localized to tumor cells bearing the TAA can then be visualized upon positron emission tomography (PET).

    (Gallium Ga 68-labeled DOTA Di-HSG Peptide IMP-288, NCI Thesaurus)




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