Editura Global Info / Dicţionar englez-român

HELIX

Pronunție (USA):

(GB):

Traducere în limba română

helix, plural helices substantiv

1. spirală, linie spirală.

2. (anat.) melc (urechea internă).

3. (tehn.) elice.

4. (zool.) melc.

5. (arhit.) volută, ornament în spirală la capitelul coloanelor.

6. (paleontologie) helix (gasteropod).

 Exemple de propoziții și/sau fraze: 

When examined from the top of the helix, there is a large hole in the middle, the sugar phosphate backbone is at the edge of the helix, and the bases are displaced towards the edge.

(A-DNA, NCI Thesaurus)

Pegylated granulocyte colony stimulating factor MAXY-G34 contains multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human G-CSF as pegylation sites; other naturally occurring lysine residues have been removed to prevent pegylation and the variant G-CSF is pegylated with methoxypolyethylene glycol succinimidyl propionate (mPEG SPA) at three amino acid residues.

(Pegylated Granulocyte Colony Stimulating Factor MAXY-G34, NCI Thesaurus)

Identified in over 240 functionally diverse proteins from yeast to man, ARM Repeats are approximately 40-amino acids long and composed of two longer anti-parallel helices (H2 and H3) that follow a perpendicular short helix (H1).

(Armadillo Repeat, NCI Thesaurus)

bHLH class proteins are sequence-specific DNA-binding proteins that contain a conserved 50-amino acid HLH domain consisting of two alpha-helices separated by a variable loop sequence, adjacent to a sequence that is highly enriched in basic amino acids.

(BHLH Protein, NCI Thesaurus)

The milatuzumab moiety of this ADC selectively binds to CD74 on tumor cell surfaces; upon internalization, the doxorubicin moiety is released, where it intercalates between base pairs in the DNA helix and inhibits topoisomerase II, thereby preventing DNA replication and increasing double-strand breakage.

(Milatuzumab-Doxorubicin Antibody-Drug Conjugate, NCI Thesaurus)

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