Editura Global Info / Dicţionar englez-român

INTERMEDIATES

Traducere în limba română

intermediates substantiv

plural semifabricate, produse intermediare.

 Exemple de propoziții și/sau fraze: 

Upon administration, melphalan is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA; RNA and proteins may also be alkylated.

(Melphalan Hydrochloride/Sulfobutyl Ether Beta-Cyclodextrin Complex, NCI Thesaurus)

Melphalan hydrochloride is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA.

(Melphalan Hydrochloride, NCI Thesaurus)

These agents also produce toxic free-radical intermediates and interact with cell membrane lipids causing lipid peroxidation.

(L-377,202, NCI Thesaurus)

Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis.

(Abiraterone, NCI Thesaurus)

During autophagy, LC3 proteins are cleaved by cysteine protease ATG4B to form LC3-I intermediates which are located in the cytoplasm.

(Microtubule-Associated Proteins 1A/1B Light Chain 3-II, NCI Thesaurus)

Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections.

(Nitrofurantoin, NCI Thesaurus)

Although the mechanism of action is unclear, phenethyl Isothiocyanate (PEITC) was shown to induce apoptosis in tumor cells, possibly mediated through its metabolic intermediates, reactive oxygen species (ROS).

(Phenethyl isothiocyanate, NCI Thesaurus)

These reactive oxygen intermediates include SINGLET OXYGEN, SUPEROXIDES, PEROXIDES, HYDROXYL RADICAL and HYPOCHLOROUS ACID.

(Oxygen radical, NLM, Medical Subject Headings)

The hydrochloride is a synthetic, light sensitive, white crystalline powder that is soluble in dimethylsulfoxide and ethanol. o-Toluidine and o-toluidine hydrochloride are used primarily as intermediates in the manufacture of dyes and pigments.

(o-Toluidine, NCI Thesaurus)

This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation.

(Detorubicin, NCI Thesaurus)

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