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    INTRAVENOUS

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    intravenous adjectiv

    (med., fiziol.) intravenos.

     Exemple de propoziții și/sau fraze: 

    Upon intravenous administration, the monoclonal antibody moiety of immunoconjugate IMGN289 binds to and inhibits EGFR on tumor cell surfaces.

    (Anti-EGFR TAP Antibody-drug Conjugate IMGN289, NCI Thesaurus)

    Upon intratumoral or intravenous administration, pexastimogene-devacirepvec may selectively infect and lyse tumor cells.

    (Pexastimogene-devacirepvec, NCI Thesaurus)

    Upon intravenous administration, MEDI4736 binds to the cell surface antigen B7H1, thereby blocking B7H1 signaling.

    (Anti-B7H1 Monoclonal Antibody MEDI4736, NCI Thesaurus)

    EXAMPLE(S): oral, intravenous.

    (Performed Substance Administration Route Of Administration Code, NCI Thesaurus/BRIDG)

    Upon intravenous or subcutaneous administration, PEG-linked L-RNA oligonucleotide hepcidin targeting agent NOX-H94 binds to hepcidin and prevents it from binding to the iron channel ferroportin, located on the basolateral surface of gastrointestinal enterocytes and the plasma membrane of macrophages.

    (PEG-linked L-RNA Oligonucleotide Hepcidin-targeting Agent NOX-H94, NCI Thesaurus)

    Upon intravenous administration of pegylated recombinant human arginase I BCT-100, arginase metabolizes the amino acid arginine to ornithine and urea, depleting intracellular arginine, which may inhibit proliferation of cells that are auxotrophic for arginine such as hepatocellular carcinoma (HCC) cells.

    (Pegylated Recombinant Human Arginase I BCT-100, NCI Thesaurus)

    Upon intravenous administration, the siRNAs in KSP/VEGF siRNAs ALN-VSP02ALN bind to both KSP and VEGF messenger RNAs (mRNAs), preventing translation of KSP and VEGF proteins; this may result in growth inhibition of tumor cells that overexpress KSP and VEGF.

    (Anti-KSP/Anti-VEGF siRNAs ALN-VSP02, NCI Thesaurus)

    More than 1100 patients underwent intensive glucose management, which required the use of intravenous delivery of insulin to bring blood sugar levels down to 80-130 mg/dL, or standard glucose control using insulin shots, which aimed to get glucose below 180 mg/dL, for up to 72 hours.

    (Researchers get a handle on how to control blood sugar after stroke, National Institutes of Health)




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