Editura Global Info / Dicţionar englez-român

LINKAGE

Pronunție (USA):

(GB):

Traducere în limba română

linkage substantiv

1. sistem de verigi.

2. racord, legătură.

3. (chim.) legătură.

4. (cib.) lanţ cinematic.

5. (electr.) înlănţuire.

6. (tehn.) mecanism cu pârghii.

 Exemple de propoziții și/sau fraze: 

Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor cell proliferation.

(Canfosfamide, NCI Thesaurus)

Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation.

(Canfosfamide Hydrochloride, NCI Thesaurus)

Following absorption, carbenicillin indanyl is rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Carbenicillin Indanyl, NCI Thesaurus)

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