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LOCUS

Pronunție (USA):

(GB):

Traducere în limba română

locus, plural loci substantiv

1. loc; poziţie. scenă.

2. (mat.) loc geometric al punctelor.

3. (cib.) hodograf.

 Exemple de propoziții și/sau fraze: 

Human CYP3A gene locus is located within 7q21.3-q22.1 and is approximately 218 kb in length.

(CYP3A Gene Locus, NCI Thesaurus)

A chromosomal translocation t(11;14)(q23;q32) of this gene and the IGH locus is associated with mediastinal large cell lymphoma.

(PCSK7 wt Allele, NCI Thesaurus)

The 110-kb EGFR gene locus encodes the EGF receptor, a cell surface transmembrane protein tyrosine kinase involved in regulation of cell growth and differentiation.

(Oncogene ERB B, NCI Thesaurus)

A variety of leukemias and lymphomas are associated with translocations t(10;14)(q24;q11) of the gene and the T-cell receptor alpha or delta locus, or t(10;14)(q24;q32) of this gene and the IGHA1 locus.

(NFKB2 wt Allele, NCI Thesaurus)

Previously, Anand Swaroop, Ph.D., chief of the Neurobiology-Neurodegeneration and Repair Laboratory at National Eye Institute and colleagues had compared populations of people with and without AMD and identified 34 small genomic regions—called loci—and 52 genetic variants within these loci that were significantly associated with AMD.

(New study about genes linked to age-related macular degeneration, National Institutes of Health)

A chromosomal deletion in the pseudoautosomal region 1 of either chromosome X or Y causing fusion of this gene with the P2RY8 gene and chromosomal translocations t(X;14)(p22;q32)/t(Y;14)(p11;q32) of this gene and the IGH locus are associated with B-cell acute lymphoblastic leukemia.

(CRLF2 wt Allele, NCI Thesaurus)

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