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MALATE

Traducere în limba română

malate substantiv

(chim.) malat (sare a acidului malic).

 Exemple de propoziții și/sau fraze: 

A malate salt of diltazem, a benzothiazepine calcium channel blocking agent.

(Diltiazem Malate, NCI Thesaurus)

First, oxaloacetate on the cytoplasmic side is reduced by NADH, creating malate and NAD+.

(Malate-Aspartate Shuttle Pathway, NCI Thesaurus/BIOCARTA)

Once in the cytosol, the citrate is converted back to oxaloacetate, which is then reduced to malate.

(Acetyl Group Shuttle Pathway, NCI Thesaurus/BIOCARTA)

Cabozantinib-s-malate blocks certain proteins, which may help keep cancer cells from growing.

(Cabozantinib-s-malate, NCI Dictionary)

The s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.

(Cabozantinib S-malate, NCI Thesaurus)

The malate salt of almotriptan, a sulfonamide triptan with vasoconstrictor activity.

(Almotriptan Malate, NCI Thesaurus)

The malate salt of amonafide, an imide derivative of naphthalic acid, with potential antineoplastic activity.

(Amonafide L-Malate, NCI Thesaurus)

Also called cabozantinib-s-malate.

(Cometriq, NCI Dictionary)

The Gly-rich NAD-Binding Domain (often N-terminal) is often found in metabolic enzymes involved in glycolysis, glyconeogenesis, and the citric acid cycle, such as GAPDH (glyceraldehyde-3-phosphate oxidation and phosphorylation), lactate dehydrogenases (lactate to pyruvate conversion), and malate dehydrogenases (malate to oxaloacetate interconversion).

(NAD-Binding Domain, NCI Thesaurus)

Malate and the electrons it carries are transported into the mitochondria across the inner mitochondrial membrane, in exchange for alpha-ketoglutarate, which is transported out of the mitochondria.

(Malate-Aspartate Shuttle Pathway, NCI Thesaurus/BIOCARTA)

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