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    METHYLATE

    Traducere în limba română

    methylate verb tranzitiv

    (chim.) a metila.

     Exemple de propoziții și/sau fraze: 

    This protein plays a role in the repression of transcription through binding methylated DNA.

    (Methyl-CpG-Binding Protein 2, NCI Thesaurus)

    The sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects.

    (Indomethacin Sodium, NCI Thesaurus)

    Dextrometorphan, a synthetic, methylated dextrorotary analogue of levorphanol, exhibits antitussive activity by activating opioid receptors in the cough center in the central nervous system, thereby raising the threshold for coughing.

    (Guaifenesin-DM, NCI Thesaurus)

    Enzyme that transfers methyl groups from O(6) methylguanine and other methylated moities of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single step reaction

    (Methylated-DNA--Protein-Cysteine Methyltransferase, NIH CRISP Thesaurus)

    First, a genomic DNA sample is amplified using adaptor oligonucleotides in which every cytosine is methylated.

    (MethylC-Seq, NCI Thesaurus)

    A methylated tyrosine, a catecholamine synthesis antagonist with antihypertensive property.

    (Metyrosine, NCI Thesaurus)

    A methylated synthetic androgen receptor agonist with anabolic effects.

    (Methyltestosterone, NCI Thesaurus)

    Gentamicin C1 has a methyl group in the 6' position of the 2-amino-hexose ring and is N methylated at the same position.

    (Gentamicin C1, NCI Thesaurus)

    The PRC complex specifically methylates nucleosomal histone H3 at lysine 27, providing an epigenetic mark for binding of PRC1 complex.

    (Gene Silencing Pathway, NCI Thesaurus/BIOCARTA)

    A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine.

    (Dextromethorphan, NCI Thesaurus)




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