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MOTILITY

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(GB):

Traducere în limba română

motility substantiv

motilitate.

 Exemple de propoziții și/sau fraze: 

This gene plays a role in both cell morphology and cell motility.

(ACTA2 Gene, NCI Thesaurus)

Two of the proteins involved in the formation of Y branches and in cell motility are Arp2 and Arp3, both members of a large multiprotein complex containing several other polypeptides as well.

(Actin Branching Pathway, NCI Thesaurus/BIOCARTA)

PI3K inhibitor GDC-0941 selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway; inhibition of tumor cell growth, motility and survival in susceptible tumor cell populations may result.

(PI3K Inhibitor GDC-0941 Bismesylate, NCI Thesaurus)

Any substance that inhibits phosphatidylinositol 3-kinase (phosphatidylinositide 3-kinase), an enzyme that catalyzes the phosphorylation of the 3 position hydroxyl group of the inositol ring of phosphatidylinositol and functions as an intracellular signal transducer in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking.

(Phosphatidylinositide 3-Kinase Inhibitor, NCI Thesaurus)

PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.

(PAK4 Inhibitor PF-03758309, NCI Thesaurus)

Alpha-2A Adrenergic Receptor (450 aa, 49 kD) is a cell motility protein that is encoded by the human ADRA2A gene and has roles in actin cytoskeletal organization, cell motility, regulation of cell proliferation and signal transduction.

(Alpha-2A-Adrenergic Receptor, NCI Thesaurus)

P70S6K, a serine/threonine kinase, acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway, is often upregulated in a variety of cancer cells, and is involved in the regulation of cell growth, proliferation, motility, and survival.

(p70S6K Inhibitor LY2584702, NCI Thesaurus)

An inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival.

(mTOR Kinase Inhibitor AZD8055, NCI Thesaurus)

Any substance that inhibits mammalian target of rapamycin (mTOR or FK506 binding protein 12-rapamycin associated protein 1 (FRAP1)), a serine/threonine protein kinase that is active in the control of cell growth, cell proliferation, and cell motility.

(mTOR inhibitor, NCI Thesaurus)

Abl interactor 2 (513 aa, 56 kD) is a cell motility process protein that is encoded by the human ABI2 gene and has roles in peptidyl tyrosine phosphorylation and cell migration, and may have additional roles in actin polymerization and depolymerization.

(ABL Interactor 2, NCI Thesaurus)

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