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    PLAQUE

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    Traducere în limba română

    plaque substantiv

    1. placă (de metal, faianţă etc.), tăbliţă.

    2. (med.) porţiune (de piele) inflamată.

    3. (amer.) emblemă (la anumite ordine).

     Exemple de propoziții și/sau fraze: 

    Over time, the neural cells secreted beta-amyloid, which formed plaques in the gel matrix.

    (Human Cells Model Alzheimer’s Disease, NIH)

    In the absence of improvement in other cardiovascular risk factors, and without adding new cholesterol medications, patients’ soft-plaque still improved.

    (Study links psoriasis treatment and improvement in heart artery disease, Editura Global Info)

    Plaque is a substance made up of fat and cholesterol.

    (Peripheral Arterial Disease, NIH: National Heart, Lung, and Blood Institute)

    Alzheimer's disease is associated with dense aggregations of proteins in the brain called amyloid plaques that contain beta-amyloid fragments as a primary component.

    (Amyloid Beta-Peptide Pathway, NCI Thesaurus/BIOCARTA)

    The proteolytic processing of Notch resembles in several ways the proteolytic processing of amyloid precursor protein (APP) that is implicated in plaque formation in Alzheimer's disease, with TACE and Presenilin-1 implicated in proteolytic processing of both Notch and APP.

    (Notch Proteolysis and Signaling Pathway, NCI Thesaurus/BIOCARTA)

    Researchers have suspected for some time that allergens can trigger certain immunological changes that might be associated with plaque buildup and artery blockages, but no one had identified a specific substance that is responsible for this effect.

    (Researchers have found a link between allergen in red meat and heart disease, National Institutes of Health)

    Alzheimer’s disease has 2 key features in brain tissue: plaques and tangles.

    (Human Cells Model Alzheimer’s Disease, NIH)

    Now researchers provided first in-human evidence that treatment of a known inflammatory condition with biologic therapy, a type of drugs that suppresses the immune system, was associated with a reduction in coronary artery disease, in particular of rupture prone plaque which often leads to a heart attack.

    (Study links psoriasis treatment and improvement in heart artery disease, Editura Global Info)

    The team found that when they blocked beta-amyloid formation, plaques didn’t develop and levels of the modified tau protein decreased.

    (Human Cells Model Alzheimer’s Disease, NIH)




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