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PROLONGING

Traducere în limba română

prolonging substantiv

1. (în timp) prelungire (a duratei unui lucru); (com.) prelungire, amânare (a unei scadenţe).

2. (în spaţiu) prelungire (a unui zid etc.).

 Exemple de propoziții și/sau fraze: 

This agent also potentiates the effects of 5-fluorouracil and its derivatives by stabilizing the binding of 5-fluorouracil's converted form fluorodeoxyuridylic acid to its target enzyme thymidylate synthase, thus prolonging drug activity.

(Leucovorin, NCI Thesaurus)

This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity.

(Leucovorin calcium, NCI Thesaurus)

Maprotiline hydrochloride exerts its effect by blocking the re-uptake of norepinephrine, thereby increasing the synaptic concentration of norepinephrine in the central nervous system and subsequently prolonging the action of norepinephrine on central receptors.

(Maprotiline Hydrochloride, NCI Thesaurus)

Although the mechanism of action has not been fully elucidated, oxazepam appears to enhance gamma-aminobutyric acid (GABA) receptor affinity for GABA, thereby prolonging synaptic actions of GABA.

(Oxazepam, NCI Thesaurus)

Upon administration, the prodrug emitefur is converted into 5-FU, while CNDP prevents the degradation of 5-FU by inhibiting DPYD and thereby prolonging the half-life of 5-FU.

(Emitefur, NCI Thesaurus)

Doxepin blocks the reuptake of norepinephrine and serotonin into presynaptic terminals thereby prolonging the availability of the monoaminergic neurotransmitters within the synaptic cleft and enhancing their action leading to sedative effects.

(Doxepin Hydrochloride, NCI Thesaurus)

The inhibition of cGMP degradation results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, thereby prolonging penile erection.

(Avanafil, NCI Thesaurus)

Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereby prevents acetylcholine hydrolysis and prolonging its activity on nicotinic receptors at the neuromuscular junction.

(Ambenonium Chloride, NCI Thesaurus)

Any agent that is capable of activating cholinergic receptors (nicotinic and muscarinic) or of enhancing or prolonging the actions of acetylcholine.

(Cholinergic Agonist, NCI Thesaurus)

Night quickly shut in, but to my extreme wonder, I found that the cottagers had a means of prolonging light by the use of tapers, and was delighted to find that the setting of the sun did not put an end to the pleasure I experienced in watching my human neighbours.

(Frankenstein, de Mary Wollstonecraft Shelley)

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