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REGULATOR
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Traducere în limba română
regulator substantiv
1. reglor, reglementator.
2. (tehn.) regulator, moderator, egalizator, compensator.
3. cronometru.
Exemple de propoziții și/sau fraze:
Viral Oncogene E1A encodes E1A Protein, a regulator of early viral gene transcription.
(Oncogene E1A, NCI Thesaurus)
Apoptosis regulator BAX (192 aa, ~21 kDa) is encoded by the human BAX gene.
(Apoptosis Regulator BAX, NCI Thesaurus)
Further experiments revealed that NASH-induced scarring depends on TGF-beta, a broad immune system regulator and target for experimental NASH therapies, and IL-13, a type 2 molecule produced by various immune cells, including eosinophils.
(NIH study sheds light on immune responses driving obesity-induced liver disease, National Institutes of Health)
The major regulator of blood pressure homeostasis is the renin-angiotensin system.
(Angiotensin-converting Enzyme 2 Pathway, NCI Thesaurus/BIOCARTA)
HIF-1alpha, normally activated in response to hypoxia-induced stress, is a key transcription regulator of a large number of genes important in cellular adaptation to low-oxygen conditions, including angiogenesis, cell proliferation, apoptosis, and cell invasion.
(Anti-HIF-1alpha LNA Antisense Oligonucleotide EZN-2968, NCI Thesaurus)
GRP78, the endoplasmic reticulum (ER) chaperone and unfolded protein response (UPR) regulator, is overexpressed on the surface of a variety of cancer cell types; its expression is associated with increased tumor cell survival and proliferation, as well as angiogenesis and resistance to chemotherapy.
(Anti-GRP78 Monoclonal Antibody PAT-SM6, NCI Thesaurus)
A single transcriptional regulator initially associated with the activation of the T-cells (NFATc4) has been shown to link genetic and environmental causes of one class of congenital heart disorders, birth defects involving valve and septum formation.
(NFAT Pathway, NCI Thesaurus/BIOCARTA)
As integral components of the late G1 restriction point, the Rb gene product and p16 are negative regulators of the cell cycle; ovarian cancer cells and non-small cell lung cancer cells may be defective in the Rb/p16 pathway.
(Oncolytic Ad5-Delta 24RGD, NCI Thesaurus)
The protein MDM2, a negative regulator of p53 activity, is overexpressed in many cancer cell types; the tumor suppressor p53 is mutated or deleted in about 50% of all cancers but active in the other 50%.
(Nutlin-3a, NCI Thesaurus)
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