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    RESIDUE

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    Traducere în limba română

    residue substantiv

    1. rest, rămăşiţă, excedent, saldo.

    2. v. residuum.

    3. (jur.) moştenire rămasă după plata datoriilor şi impozitelor.

     Exemple de propoziții și/sau fraze: 

    Aldesleukin binds to and activates the IL-2 receptor, followed by heterodimerization of the cytoplasmic domains of the IL-2R beta and gamma(c) chains; activation of the tyrosine kinase Jak3; and phosphorylation of tyrosine residues on the IL-2R beta chain, resulting in an activated receptor complex.

    (Aldesleukin, NCI Thesaurus)

    Remember to distance yourself from the start and end dates of the retrograde. (There is always residue debris found on the days right before and after the dates of the retrograde period, which is best to avoid.)

    (AstrologyZone.com, de Susan Miller)

    A site on a protein that is a target for enzymatic cleavage, where the residue on the amino terminal side of the cleavage site is a basic amino acid that is not adjacent to other basic amino acids.

    (Monobasic Proteolytic Cleavage Site, NCI Thesaurus)

    After cell entry, the first 12 amino acid residues interact with tumor suppressor p53 and form a p28:p53 complex, which may result in a reduction of proteasomal degradation of p53, increased p53 levels, and p53-mediated cell cycle inhibition and apoptosis.

    (Azurin:50-77 Cell Penetrating Peptide p28, NCI Thesaurus)

    The proprietary humanized catalytic IgG1 monoclonal aldolase antibody contains reactive lysine residues in its binding sites, which react covalently with compounds having a diketone function; the Ang2 and VEGFR peptide moieties are then covalently attached to the diketone linkers via a proprietary spacer.

    (Ang2/VEGF-Binding Peptides-Antibody Fusion Protein CVX-241, NCI Thesaurus)

    An immunoconjugate consisting of a humanized monoclonal antibody that is engineered to contain cysteine residues that are conjugated to the synthetic, DNA cross-linking, pyrrolobenzodiazepine dimer SGD-1882, via the protease-cleavable linker maleimidocaproyl-valine-alanine dipeptide, with potential antineoplastic activity.

    (Anti-CD33 Antibody-Drug Conjugate SGN-CD33A, NCI Thesaurus)

    The resulting bioactive mono-alkyltriazene species are capable of alkylating nucleophilic residues in the immediate vicinity such as N-7 and/or O-6 sites of guanine, thereby causes intra- or inter-stranded DNA cross-links and trigger apoptosis.

    (Mitozolomide, NCI Thesaurus)




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