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    UROTOXIC

    Traducere în limba română

    urotoxic adjectiv

    (med.) urotoxic.

     Exemple de propoziții și/sau fraze: 

    In the kidney, dimesna undergoes reduction to the free thiol compound, mesna, which reacts chemically with the urotoxic ifosfamide metabolites acrolein and 4-hydroxy-ifosfamide, resulting in their detoxification.

    (Dimesna, NCI Thesaurus)

    Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion.

    (Mesna, NCI Thesaurus)




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