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    ZETA

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    zeta substantiv

    zeta (literă in alfabetul grecesc).

     Exemple de propoziții și/sau fraze: 

    Autologous peripheral blood T-lymphocytes (PBTLs) transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) consisting of an anti-CD19 scFv (single chain variable fragment) coupled to the costimulatory signaling domain CD28, the signaling domain of 4-1BB (CD137), and the zeta chain of the T-cell receptor (TCR), with potential immunomodulating and antineoplastic activities.

    (Autologous PBTL CD19CAR-28/CD137/zeta, NCI Thesaurus)

    A preparation of autologous peripheral blood T-lymphocytes (PBTL) that have been genetically modified to express the chimeric antigen receptor (CAR) anti-CD19/CD3 zeta chain fusion protein coupled to the intracellular signal domain of CD28 antigen, with potential immunostimulating and antineoplastic activities.

    (Autologous PBTL CD19CAR-28 zeta, NCI Thesaurus)

    Allogeneic T-lymphocytes transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) consisting of an anti-CD19 scFv (single chain variable fragment) coupled to the costimulatory signaling domain CD28, the signaling domain of 4-1BB (CD137), and the zeta chain of the T-cell receptor (TCR), with potential immunomodulating and antineoplastic activities.

    (CD19CAR-CD28zeta-4-1BB-expressing Allogeneic T Lymphocytes, NCI Thesaurus)

    Allogeneic natural killer (NK) cells transduced with an mRNA expressing a chimeric antigen receptor (CAR) consisting of an anti-CD19 scFv (single chain variable fragment) and the zeta chain of the TCR/CD3 complex (CD3-zeta), coupled to the signaling domain of 4-1BB (CD137), with potential immunomodulating and antineoplastic activities.

    (Anti-CD19-CAR-CD3zeta-4-1BB-Expressing Allogenic Natural Killer Cells, NCI Thesaurus)

    A preparation of autologous peripheral blood T-lymphocytes (PBTL) that have been genetically modified to express a chimeric antigen receptor (CAR) consisting of an anti-CD19 scFv (single chain variable fragment) coupled to the costimulatory signaling domain CD28 and the zeta chain of the T-cell receptor (TCR)/CD3 complex (CD3 zeta), with potential immunostimulating and antineoplastic activities.

    (Anti-CD19-CAR Retroviral Vector-Transduced Autologous T Cells, NCI Thesaurus)

    A preparation of autologous blood T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) consisting of an anti-CD20 scFv (single chain variable fragment); the cytoplasmic portion of the human TCR-[zeta] molecule; and the co-stimulatory molecule 4-1BB (CD137), with potential immunostimulating and antineoplastic activities.

    (Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells, NCI Thesaurus)

    Autologous T-lymphocytes transduced with a modified lentiviral vector expressing a chimeric antigen receptor (CAR) consisting of an anti-CD19 scFv (single chain variable fragment) and the zeta chain of the TCR/CD3 complex (CD3-zeta), coupled to the signaling domain of 4-1BB (CD137), with potential immunomodulating and antineoplastic activities.

    (CD19CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes, NCI Thesaurus)

    The 4-1BB co-stimulatory molecule signaling domain enhances activation and signaling after recognition of CD20; the inclusion of this signaling domain may increase the antitumor activity compared to the inclusion of the CD3-zeta chain alone.

    (Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells, NCI Thesaurus)




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